Advanced Life Sciences Announces Appointment of Financial Executive
to Board of Directors

Woodridge, Ill, June 25, 2001 - Advanced Life Sciences, Inc. announced today the appointment of Kathryn Burrer Hyer, JD, to its Board of Directors. Ms. Hyer is an accomplished businesswoman and senior financial executive whose most recent position was Chief Financial Officer of Quark Biotech, Inc. in Chicago, Illinois.

"We are extremely pleased that a business person with as many accomplishments as Ms. Hyer has, has joined our Board of Directors," said Dr. Sharon W. Ayd, Chief Operating Officer of Advanced Life Sciences. "Kathryn Hyer has impressive credentials and many years of successful experience in analyzing business potential and in raising large sums of financing. These talents are precisely what we need to ensure that our company is successful in raising venture capital, vital in sustaining our business model."

Ms. Hyer graduated Magna Cum Laude from Aquinas College, Grand Rapids, Michigan and received a law degree from the Marshall College of Law at Cleveland State University. Prior to her position at Quark Biotech, Ms. Hyer was Managing Director, Health Care Group at Everen Securities, Inc., Chicago, Illinois where she identified financing, strategic partnerships and acquisition opportunities. She also managed initial public offerings and acted as sole agent in private placements. In just two years she generated over $10 million in fees. Ms. Hyer was also Director of Finance for the City of Cleveland, Ohio where she managed a $1 billion budget in the Office of Budget & Management.

Advanced Life Sciences, Inc., based in Woodridge, Illinois ( is a privately held, early-stage pharmaceutical technology development company that discovers and develops therapeutic compounds to fight infection, inflammation and cancer. The company bridges the gap between academic discoveries and pharmaceutical commercialization and focuses on conditions that have significant unmet medical needs in medium sized markets.

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