Contact: Edward P. Flavin (630-739-6744 Ex211)

 

Advanced Life Sciences Announces Filing of Initial Public Offering

 

Woodridge, Ill, April. 28, 2005 - Advanced Life Sciences Holdings, Inc. announced today that it filed a registration statement with the Securities and Exchange Commission for a proposed initial public offering of its common stock. The number of shares to be offered and the price range for the offering have not yet been determined.

C.E. Unterberg, Towbin, LLC will serve as sole bookrunning manager, with Think Equity Partners, LLC acting as co-lead manager for the proposed offering.

Advanced Life Sciences is a biopharmaceutical company engaged in the discovery, development and commercialization of novel drugs in the therapeutic areas of infection, cancer, and inflammation using its platform in natural products and chemical proteomics coupled with expertise in drug development.

A registration statement relating to these securities has been filed with the Securities and Exchange Commission but has not yet become effective. These securities may not be sold nor may offers to buy be accepted prior to the time the registration statement becomes effective. This press release shall not constitute an offer to sell or the solicitation of an offer to buy nor shall there be any sale of these securities in any state in which such offer, solicitation or sale would be unlawful prior to registration or qualification under the securities laws of any such state.

A copy of the prospectus relating to these securities may be obtained, when available, from C.E. Unterberg, Towbin, LLC, 350 Madison Avenue, New York, NY 10017

This press release includes “forward-looking statements" within the meaning of the Securities Litigation Reform Act of 1995. These statements include but are not limited to our plans, objectives, expectations and intentions and other statements that contain words such as “expects,” “contemplates,” “anticipates,” “plans,” “intends,” “believes” and variations of such words or similar expressions that predict or indicate future events or trends, or that do not relate to historical matters. These statements are based on our current beliefs or expectations and are inherently subject to significant uncertainties and changes in circumstances, many of which are beyond our control. There can be no assurance that our beliefs or expectations will be achieved. Actual results may differ materially from our beliefs or expectations due to economic, business, competitive, market and regulatory factors.

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